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KMID : 0363319970180020195
Journal of Korean Oriental Internal Medicine
1997 Volume.18 No. 2 p.195 ~ p.206
The effects of Ohwangsahwa-Tang(Wu-Huang-Xie-Huo-Tang) on Hypercholesterolemia Rats induced by 2% Chole- sterol Fed-Diet
Jang Yong-Soo

Ko Chang-Nam
Cho Ki-Ho
Kim Young-Suk
Bae Hyung-Sup
Lee Kyung-Sub
Abstract
In order to study the effects of Ohwangsahwatang on Hyperchole-sterolemia, experimental study were performed on Hypercholesterolemia Rats induced by 2% cholesterol diet. Also the level of total cholesterol. triglyceride, LDL-cholesterol. HDL-cholesterol, phospholipid, transami-nase(GOT, GPT) were measured. The results were summerized as follows : In the model of Hypercholesterolemia induced by 2% cholesterol diet in rats, Ohwangsahwatang showed decreasing effects on total cholesterol, triglyceride, LDL-cholesterol, phospholipid level, and transaminase (GOT, GPT) activity in serum significantly, depending on the concentration, and showed increasing effects on HDL-cholesterol level in serum significantly depending on the concentration. According to the above results, Ohwangsahwatang showed significant decreasing effects on Hypercholesterolemia, and it is considered that it is appropriate to apply for Hypercholesterolemia.
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